ASCEND
Week 108
As I said in my previous post for week 104 I am finishing the ASCEND trial. 2 October 2014 is my last visit to the clinical research center. Why did I stop I could continue and definitely receive Tysabri (natalizimubab) but the risk of my getting PML is too high for me to continue. This is […]
Week 96
Slowly but surely the weeks trickle by. Only another 12 weeks until the trial finally finishes. That’s another 3 visits to the Royal London Hospital. Even at this stage I don’t know if I’m receiving the real deal or a placebo. It is a random double blind trial. I suspect that I am receiving the […]
Week 84
Its now week 84 of the ASCEND trial, the weeks seems to have have rolled by ever so quickly. I can’t believe I’m nearly at the end. The real thing? Even after week 84 I have no idea whether I’m on a placebo or not. Looking back over the months of the trial my balance […]
ASCEND trial, week 72
Three quarters of the way there On Wednesday 22 Jan I had another infusion for the ASCEND trial, week 72, my 18th infusion of tysabri. Its a 96 week trial, so 24 weeks to go, 6 more infusions. Am I on a placebo? Nobody knows, this is because it is a double blinded trial. […]
Diagnosis, what next?
You have been diagnosed with Relapsing Remitting Multiple Sclerosis (RRMS), this happened to me in 1995. How many of you have been offered a disease modifying therapy (DMT) and when were you diagnosed? You try disguising a fall When I was diagnosed with MS I was not offered any treatment because none was available. I […]
48 weeks, half way there
I have been on the ASCEND trial for 48 weeks, half way through, so that’s another 12 more infusions. Could Biogen Idec have a treatment for secondary progressive multiple sclerosis (SPMS)? I have spent the last two days up at the Royal London hospital having tests.Yesterday (Monday) was taken up with assessing my EDSS […]
Oh dear, not again
Oh dear, not again. I lose my reading reading glasses. It was going to be a long day An early start means catching a train at into London at about eight in the morning and arrive back home at about six. As well as the infusion a batch of tests to include various timed walks, […]
Week 24
I have been a bit lazy writing reports on the ASCEND trial, better later than never is all I can say. What stopped me? Actually it was finding something that was worth writing about. This takes a slightly different slant from the previous articles. Every four weeks I need to get out of bed at […]
Third infusion
My third infusion was on 31 October, that was a few days ago. Double vision was troubling me when I went up the previous time, so I went to my optician, he told me to wear my reading glasses more often. Now I have no trouble with the double vision problem when doing work on […]
Second infusion
Today I went the Royal London hospital and had my second infusion. There was not a lot to report since my first infusion. I have not noticed any difference in the last 4 weeks except that my double vision has got worse. This time there was just one test. I was shown a list of […]
First Infusion 4th September
The infusions are to done monthly and the first one must be within 6 weeks of being accepted for the trial. I was accepted on 26th July. The first infusion It was set for Tuesday 4th September, cutting it a bit fine, but hey-ho I made it. I was told the first day would be […]
Ascend Trial, the screening
MS is a progressive autoimmune disease and so far no cure has been found. It is devastating; you just gradually lose the ability to control part or parts of your body. Ascend trial, the screening My left leg has no strength. generally speaking from the wast down I’m a bit of a disaster. At least […]
